Diabetes drug may help treat breast cancer: Chinese researchers » Manila Bulletin Lifestyle

Manila Bulletin Philippines

Breaking News from the Nation's leading newspaper

Tempo

Online Newspaper

Showbiz and Celebrity News

Sports News

World News
News Asia

The Nation's Leading Newspaper

Tuesday, September 19, 2017 27° Partly cloudy

Diabetes drug may help treat breast cancer: Chinese researchers

Published

By Philippine News Agency

Researchers in China have discovered that a drug used to treat diabetes could be effective against a form of deadly breast cancer.

More than 70,000 people die from breast cancer in China every year, according to the national cancer center.

Credit: Pixabay / MANILA BULLETIN

Credit: Pixabay / MANILA BULLETIN

Triple-negative breast cancer is particularly aggressive among the four clinical subtypes of breast cancer, said Dong Chenfang, a professor at Zhejiang University School of Medicine. It has a tendency to quickly spread or metastasize to the brain and lungs.

There are currently no effective targeted therapies for this form of breast cancer, which is therefore often fatal, according to Dong.

Dong and his colleagues found that the levels of a metabolic enzyme called AKR1B1 were significantly elevated in triple-negative breast cancer cells and that this was associated with increased rates of metastasis and shorter survival times.

The researchers also found epalrestat, a drug that inhibits AKR1B1 and is approved in Japan to treat diabetic complications, was able to block the growth and metastasis of the cancer cells.

Dong said the finding is still in the experimental stage. Whether epalrestat can be applied to the clinical treatment still needs further tests.

A detailed research article was published on March 7 in the Journal of Experimental Medicine.

Tags: , , , , , , ,

Related Posts

  • Edna

    Very great drug. I was diagnosed with type 2 Diabetes and put on Metformin on June 26th, 2016. I started the ADA diet and followed it 100% for a few weeks and could not get my blood sugar to go below 140. Finally i began to panic and called my doctor, he told me to get used to it. He said I would be on metformin my whole life and eventually insulin. At that point i knew something wasn’t right and began to do a lot of research. Then I found Lisa’s diabetes story (google ” HOW EVER I FREED MYSELF FROM THE DIABETES ” ) I read that article from end to end because everything the writer was saying made absolute sense. I started the diet that day and the next morning my blood sugar was down to 100 and now i have a fasting blood sugar between Mid 70’s and the 80’s. My doctor took me off the metformin after just three week of being on this lifestyle change. I have lost over 30 pounds and 6+ inches around my waist in a month. The truth is we can get off the drugs and help myself by trying natural methods